The p53 Gene and Cancer . Students learn about the structure of the protein encoded by p53 and how it normally functions to regulate cell division. On slide 1, “p53” is referred to as a molecule, a protein, and a gene; it is also referred to as being mutated.
p53 Cancer Learn Worksheet Tumor Suppressor Gene Gene from the p53 gene and cancer student worksheet answers , source:Scribd.com. The P53 Gene and Cancer Student Worksheet Answers or Mutations and Genetic Variability 1 What is Occurring In the. 7. There are two types of genes that are important in the development and growth of cancers: oncogenes and tumor suppressor genes. 1.
Most often, an accumulation of mutations in bothoncogenes and tumor suppressor genes is responsible for the development of cancer.
It is not one disease, but a collection of related diseases that can occur almost anywhere in the body. It then explores one tumor suppressor gene, p53, and its role in cancer in more depth. You can also use this The accompanying worksheets guide students’ exploration. 4. p53 is sometimes called “the guardian of the genome,” and many cancer cells harbor mutations in this gene. Why do you think this is the case?
www.BioInteractive.org Published August 2014 Revised May 2016 Page 2 of 3 Student HandoutClick and Learn The p53 Gene and Cancer Advanced c. What is required for a cell to “spin out of control”? Yes, cancers will probably not occur. A: If an extra copy of an oncogene or a missing copy of a tumor suppressor gene upsets that balance, the daughter cell might divide inappropriately, leading to cancer. Students learn about the structure of the protein encoded by p53 and how it normally functions to regulate cell division. Why is p53 called the “guardian of the genome”? In your own words, and based on your knowledge of molecular genetics, how are these terms related? It then explores one tumor suppressor gene, p53, and its role in cancer in more depth. The accompanying worksheets guide students’ exploration. 5. Answer the following questions as you proceed through the activity slides. 6. It is caused by several different factors.
What three conditions or factors activate p53 to shut down cell division (slide 3)? The final result is at the right time of evaluation, there’s a great deal of confusion.